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業績 - 学術論文 >>> 学会発表
2009
- M. Otsuka and I. Yamane, Prediction of Tablet Properties Based on Near Infrared Spectra of Raw Mixed Powders by Chemometrics: Scale-Up Factor of Blending and Tableting Processes, J. Pharm. Sci.;98(11):4296-305 (2009) .
- M. Fujimoto, K. Mihara, J. A. Jorgenson , K. Otsuka, M. Aburada, T. Kawada, J. Ishizaki, K. Miyamoto, M. Otsuka, Effects of the Position of the Paddle Shaft on the Dissolution Rates of Sodium Diclofenac Tablets and the Equivalence Assessment of the Generic product, Dissol. Tech., 16(4), 29-34 (2009).
- M. Otsuka, K. Ibe, Y. Tokudome, H. Ohshima, Nano- and Macro-Geometrical Structural Change of Caffeine and Theophylline Anhydrate Tablets during Hydration Process by using X-ray Computed Tomography,Colloids and Surfaces B: Biointerfaces, 73, 351–359 (2009).
- H. Shinzawa, K. Awa, T. Okumura, S. Morita, M. Otsuka, Y. Ozaki, H. Sato, Raman Imaging Analysis of Pharmaceutical Tablets by Two-Dimensional (2D) Correlation Spectroscopy, Vibrational Spectroscopy, 51, 125-131 (2009).
- Y. Tokudome, H. Ohshima, M. Otsuka, Non-invasive and Rapid Analysis for Observation of Internal Structure of Press-Coated Tablet using X-ray Computed Tomography, Drug Devel. Ind. Pharm., 35(6): 678-682 (2009).
- Y. Tokudome, M. Otsuka, A. Ito, R. Z. LeGeros, Long-Term Therapeutic Effect of Novel Calcium Phosphate-based Compounds Injected in Ovariectomized Rats, J. Biomed. Mat. Res. Part B: Applied Biomaterials, 90(1):229-237 (2009).
- Y. Mohri, Y. Sakata and M. Otsuka, Quantitative evaluation of glycyrrhizic acid that affects the product quality of Kakkonto extract, a traditional herbal medicine, by chemometrical NIR spectroscopic method, J. Near Infrared Spectrosc. 17, 89-100 (2009).
- Y. Sakata, M. Otsuka, Evaluation of Relationship between Molecular Behaviour and Mechanical Srenght of Pullulan films, Int. J. Pharm., 374, 33-38 (2009),
- M. Otsuka, Y. Fukui, K. Ozaki, Comparative Evaluation of Bioactivity of Crystalline Trypsin for Drying Process by Fourier-Transformed Infrared Spectroscopy, Colloids and Surfaces B: Biointerfaces, 69(2), 194-200 (2009).
- H. Kakuda, T. Okada, M. Otsuka, K. Katsumoto, T. Hasegawa, Multivariate analysis of DSC-XRD simultaneous measurement data: A Study of Multistage Crystalline Structure Changes in a Linear Poly(ethylene imine) Thin Film, Analytical and Bioanalytical Chemistry, 393(1), 367-376 (2009).
2008
- K. Shinsako, Y. Okui, Y. Matsuda, J. Kunimasa, M. Otsuka, Effects of Bead Size and Polymerization in PMMA Bone Cement on Vancomycin Release, Bio-Medical Mat. Eng., 18, 377-385 (2008).
- K. Papangkorn, G. Yan, D. D. Heslop, K. Moribe, A. A. Baig, M. Otsuka, W. I. Higuchi, Influence of Crystallite Microstrain on Surface Complexes Governing the Metastable Equilibrium Solubility Behavior of Carbonated Apatites, J. Colloid and Interface Science, 320(1), 96-109, (2008).
- K. Awa, T. Okumura, H. Shinzawa, M. Otsuka, Y. Ozaki, Self-Modeling Curve Resolution (SMCR) Analysis of Near-Infrared (NIR) Imaging Data of Pharmaceutical Tablets, Analytica Chimica Acta, 619, 81-86 (2008).
- S. Kanou, K. Nishimura, M. Ichikawa, J. Yoshida, Y. Sakata, M. Otsuka, Effect of Dehydration and Urea on Stability of Homosulfamine in Solid States, Drug Dev. Ind. Pharm., 34, 771-780 (2008).
- M. Suda, K. Takayama, M. Otsuka, An Accurate Quantitative Analysis of Polymorphic Content by Chemometric X-ray Powder Diffraction,Anal. Sci., 24, 549-557(2008).
- M. Otsuka, A. Oshinbe, R. Z. LeGeros, Y. Tokudome, A. Ito, K. Otsuka, W. I. Higuchi, Efficacy of the Injectable Calcium Phosphate Ceramics Suspensions Containing Magnesium, Zinc and Fluoride on the Bone Mineral Deficiency in Ovariectomized Rats, J. Pharm. Sci., 97 (1), 421-432 (2008).