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過去の業績

  このページでは FD-LC-MS/MS 法に関して報告した業界誌/論文をまとめました。





業界誌

1. 一番ヶ瀬智子、今井一洋(2015); 疾病メカニズム解明のためのプロテオーム解析法の開発. 薬事日報 第 11545 号、研究戦略 YAKU 学 No. 90.
薬事日報, 2015/3/9, p5.pdf

2. 今井一洋(2013); 「大きな夢,小さな夢,そして我欲へ!」[Big dream, small dream and fi nally ego!]. 技術機関誌 SI NEWS VOL.56 No.1: 1-2.
SI NEWS Vol.56 No.1(March 2013).pdf

3. 今井一洋(2013);「他人のやらないことをやれ!」「BE CREATIVE!」業界情報誌 Labcab VOL.4, Special column 17-20.
Lavcab_vol.4_2013_Sep.pdf



単行本

1. Editor(s): Kazuhiro Imai; Sam Li Fong Yau(2013); "Quantitative Proteome Analysis: Methods and Applications ". 出版社: Pan Stanford Publishing; 1版 (2013/7/31).
ISBN-10: 9814316512
ISBN-13: 978-9814316514
CRC Press ホームページへジャンプ

"amazon.co.jp" で "Quantitative Proteome Analysis: Methods and Applications " と入力すると、第一章のみ閲覧できます。

Koshiyama A, Ichibangase T, Imai K (2013); Fluorogenic derivatization followed by HPLC quantification and final identification of proteins by HPLC-tandem mass spectrometry (FD-LC-MS/MS) method. Quantitative Proteome Analysis: Methods and Applications: Pan Stanford Publishing, Singapore, 1-12



日本語総説

1. 今井一洋(2015):トップダウンプロテオーム解析法の開発と応用.臨床化学, 44, 316-324.

2. 一番ヶ瀬智子(2015):発蛍光標識化タンパク質の網羅定量解析法の開発と応用.分析化学(Bunseki Kagaku), 64, 511-517.

3. Ichibangase T, Imai K (2015): Development and Application of FD-LC-MS / MS Proteomics Analysis Revealing Protein Expression and Biochemical Events in Tissues and Cells. yakugaku zasshi 135: 197-203.

4. 今井一洋,一番ヶ瀬智子(2014):網羅定量プロテオーム解析(FD-LC-MS/MS 法)によるバイオマーカー探索. 医学のあゆみ,251,1029-1034.

5. K. Imai, T. Ichibangase (2009): 新しいプロテオーム解析法,FD-LC-MS/MS法の展開. Tanpakushitsu Kakusan Koso, 54, 754-760.



コラム

1. 今井一洋(2016):学術貢献賞受賞 豊岡利正氏の業績. ファルマシア, 52(5),443.

2. 今井一洋(2015):学術貢献賞受賞 早川和一氏の業績. ファルマシア, 51(4),366.



論文

1. Chou CK, Huang YS, Lin, Pei Yu, Imai K, Chen SM, Lee JA(2021);The Ginsenoside Rg1 Rescue Mitochondrial Disorders in Aristolochic Acid-Induced Nephropathic Mice. Life 11(10). doi:10.3390/life11101018.

2. Kobayashi H, Imai K(2021);Recent Progress in FD-LC-MS/MS Proteomics Method. Front. Chem., 04 June 2021. doi:10.3389/fchem.2021.640336 .

3. Chang HT, Lin TY, Lin CY, Tsai PY, Imai K, Chen CM, Lee JA(2020); Methylglyoxal and D-lactate in cisplatininduced acute kidney injury: Investigation of the potential mechanism via fluorogenic derivatization liquid chromatography-tandem mass spectrometry (FD-LC-MS/MS) proteomic analysis.PLoS ONE 15(7):e0235849.doi:10.1371/journal.pone.0235849.

4. Chen SM, Lin CE, Chen HH, Cheng YF, Cheng HW, Imai K(2020); Effect of prednisolone on glyoxalase 1 in an inbred mouse model of aristolochic acid nephropathy using a proteomics method with fluorogenic derivatization-liquid chromatography-tandem mass spectrometry. PLoS ONE 15(1): e0227838. doi:10.1371/journal.pone.0227838.

5. Lee MC, Cheng KJ, Chen SM, Li YC, Imai K, Lee CM, Lee JA (2019);A novel preventive mechanism of gentamicin-induced nephrotoxicity by atorvastatin.Biomed Chromatogr.33(11):e4639. doi: 10.1002/bmc.4639.

6. Lin CE, Chang WS, Lee JA, Chang TY, Huang YS, Hirasaki Y, Chen HS, Imai K, Chen SM(2018); Proteomics analysis of altered proteins in kidney of mice with aristolochic acid nephropathy using the fluorogenic derivatization-liquid chromatography-tandem mass spectrometry method. Biomed Chromatogr.32(3). doi: 10.1002/bmc.4127.

7. Nakata K, Saitoh R, Ishigai M, Imai K (2018); A proteomics method using immunoaffinity fluorogenic derivatization-liquid chromatography/tandem mass spectrometry (FD-LC-MS/MS) to identify a set of interacting proteins. Biomed Chromatogr.32(2). doi: 10.1002/bmc.4063.

8. Mori M, Ichibangase T, Yamashita S, Kijima-Suda I, Kawahara M, Imai K(2015)Quantification of horse plasma proteins altered by xylazine using the fluorogenic derivatization-liquid chromatography-tandem mass spectrometry. J Equine Sci 26: 141-146.

9. Ichibangase T, Imai K (2014) Straightforward proteomic analysis reveals real dynamics of proteins in cells. J Pharm Biomed Anal 101: 31-39.

10. Nakata K, Ichibangase T, Saitoh R, Ishigai M, Imai K (2015) A trial proteomics fingerprint analysis of HepaRG cells by FD-LC-MS/MS. Analyst 140: 71-73.

11. Nakata K, Saitoh R, Amano J, Ichibangase T, Ishigai M, et al. (2014) Comprehensive and temporal analysis of secreted proteins in the medium from IL-6 exposed human hepatocyte. Biomed Chromatogr 28: 742-750.

12. Ichibangase T, Nakata K, Imai K (2014) Improved separation of fluorogenic derivatized intact proteins with high resolution and efficiency using a reversed-phase liquid chromatographic system. Biomed Chromatogr 28: 862-867.

13. Ichibangase T, Yazawa I, Imai K (2013); Efficient chromatographic separation of intact proteins derivatized with a fluorogenic reagent for proteomics analysis. Biomed Chromatogr. 27: 1520-1523.

14. Koshiyama A, Ichibangase T, Imai K (2013); Comprehensive fluorogenic derivatization-liquid chromatography/tandem mass spectrometry proteomic analysis of colorectal cancer cell to identify biomarker candidate. Biomed Chromatogr. 27: 440-450.

This publicaation was highlighted in the Target Intelligence Service (TIS), a database used by pharmaceutical companies worldwide to identify groundbreaking research on potential drug targets. Target Intelligence Service CASE REPORT.pdf

15. Tsai PY, Chen SM, Chen HY, Li YC, Imai K, et al. (2013); Proteome analysis of altered proteins in streptozotocin-induced diabetic rat kidney using the fluorogenic derivatization-liquid chromatography-tandem mass spectrometry method. Biomed Chromatogr. 27: 382-389.

16. Imai K, Ichibangase T, Nakata K (2012); Extended use of FD-LC-MS/MS method in proteome science. Luminescence 27: 538.

17. Ichibangase T, Sugawara Y, Yamabe A, Koshiyama A, Yoshimura A, Enomoto T, Imai K (2012); An FD-LC-MS/MS Proteomic Strategy for Revealing Cellular Protein Networks: A Conditional Superoxide Dismutase 1 Knockout Cells. PLOS ONE 7: e45483-e45483. http://dx.plos.org/10.1371/journal.pone.0045483

18. Ichibangase T, Imai K (2012); FD-LC-MS/MS Method for Determining Protein Expression and Elucidating Biochemical Events in Tissues and Cells. Biol Pharm Bull 35: 1393-1400.

19. Nakata K, Saitoh R, Amano J, Koshiyama A, Ichibangase T, et al. (2012); Alteration of intracellular secretory acute phase response proteins expressed in human hepatocyte induced by exposure with interleukin-6. Cytokine 59: 317-323.

20. Ohyama K, Shiokawa A, Ito K, Masuyama R, Ichibangase T, et al. (2012); Toxicoproteomic analysis of a mouse model of nonsteroidal anti-inflammatory drug-induced gastric ulcers. Biochem Biophys Res Commun 420: 210-215.

21. Koshiyama A, Ichibangase T, Moriya K, Koike K, Yazawa I, et al. (2011); Liquid chromatographic separation of proteins derivatized with a fluorogenic reagent at cysteinyl residues on a non-porous column for differential proteomics analysis. J Chromatogr A 1218: 3447-3452.

22. Imai K, Koshiyama A, Nakata K (2011); Towards clinical proteomics analysis. Biomed Chromatogr 25: 59-64.

23. Ohyama K, Tomonari M, Ichibangase T, To H, Kishikawa N, et al. (2010); A toxicoproteomic study on cardioprotective effects of pre-administration of docetaxel in a mouse model of adriamycin-induced cardiotoxicity. Biochem Pharmacol 80: 540-547.

24. Koshiyama A, Imai K (2010); Synthesis and evaluation of a fluorogenic reagent for proteomic studies: 7-fluoro-N-[2-(dimethylamino)ethyl]-2,1,3-benzoxadiazole-4-sulfonamide (DAABD-F). Analyst 135: 2119-2124.

25. Ichibangase T, Moriya K, Koike K, Imai K (2009); Limitation of immunoaffinity column for the removal of abundant proteins from plasma in quantitative plasma proteomics. Biomed Chromatogr 23: 480-487.

26. Ichibangase T, Imai K (2009); Application of fluorogenic derivatization-liquid chromatography-tandem mass spectrometric proteome method to skeletal muscle proteins in fast Thoroughbred horses. J Proteome Res 8: 2129-2134.

27. Imai K, Ichibangase T, Saitoh R, Hoshikawa Y (2008); A proteomics study on human breast cancer cell lines by fluorogenic derivatization-liquid chromatography/tandem mass spectrometry. Biomed Chromatogr 22: 1304-1314.

28. Asamoto H, Ichibangase T, Uchikura K, Imai K (2008); Application of an improved proteomics method, fluorogenic derivatization-liquid chromatography-tandem mass spectrometry, to differential analysis of proteins in small regions of mouse brain. J Chromatogr A 1208: 147-155.

29. Ichibangase T, Saimaru H, Takamura N, Kuwahara T, Koyama A, et al. (2008); Proteomics of Caenorhabditis elegans over-expressing human alpha-synuclein analyzed by fluorogenic derivatization-liquid chromatography/tandem mass spectrometry: identification of actin and several ribosomal proteins as negative markers at early Parkinson's disease stages. Biomed Chromatogr 22: 232-234.

30. Ichibangase T, Moriya K, Koike K, Imai K (2007); A proteomics method revealing disease-related proteins in livers of hepatitis-infected mouse model. J Proteome Res 6: 2841-2849.

31. Saimaru H, Yasui E, Takamura N, Imai K (2006); Synthesis and evaluation of fluorogenic reagents for simultaneous detection of peptides and proteins by HPLC in two different samples. Biomed Chromatogr 20: 576-584.

32. Masuda M, Saimaru H, Takamura N, Imai K (2005); An improved method for proteomics studies in C. elegans by fluorogenic derivatization, HPLC isolation, enzymatic digestion and liquid chromatography--tandem mass spectrometric identification. Biomed Chromatogr 19: 556-560.

33. Masuda M, Toriumi C, Santa T, Imai K (2004); Fluorogenic derivatization reagents suitable for isolation and identification of cysteine-containing proteins utilizing high-performance liquid chromatography-tandem mass spectrometry. Anal Chem 76: 728-735.

34. Toriumi C, Imai K (2003); An identification method for altered proteins in tissues utilizing fluorescence derivatization, liquid chromatography, tandem mass spectrometry, and a database-searching algorithm. Anal Chem 75: 3725-3730.








FD-LC-MS/MS 法とは?  過去の業績  研究活動報告




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